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7星彩18119期:Angiotensin II human人血管緊張素 II

DETAIL

Angiotensin II human人血管緊張素 II

¥ 410元

410元

詳細信息

体彩7星彩18095 www.jbjtkn.com.cn   產品描述

  Amino Acid Sequence

  Asp-Arg-Val-Tyr-Ile-His-Pro-Phe

  Antibody Adsorbant

  Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH · 2CH3COOH · H2O

  Analysis Note

  肽含量不低于 75%

  Application

  • Angiotensin II (angII) human has been used to study its effect on interleukin-1β–mediated islet inflammation and β-cell dysfunction.[8]

  • It has been used to determine if angII activates specific calcineurin-dependent NFAT (nuclear factor of activated T-cells) isoforms in cardiomyocytes.[9]

  • It has been used to study the actions of systemic angII infusions on glomerular permeability in vivo.[1]

  • It has been used to check the effects of angII on plasma triglyceride production and its association with insulin resistance in normal rats.[10]

  Biochem/physiol Actions

  Angiotensin II (angII) is an octapeptide hormone which affects the activities of heart, kidney, vasculature and brain. AngII in blood is produced from angiotensinogen via renin and angiotensin converting enzyme (ACE). It works via binding to specific receptors present on cell membranes. AngII is a component of the renin-angiotensin system. It is associated with vasoconstriction, induction of vascular smooth muscle cell growth, stimulation of protooncogene expression, modulation of myocardial hypertrophy, renal failure and fibrosis.[2][3][4][5][6][7]

  溫馨提示:不可用于臨床治療。

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